vQ: What is cancer chemotherapy?
Cancer chemotherapy refers to the use of drugs to treat cancer. Chemotherapy drugs collectively referred to as anti-cancer drug. Cancer treatment methods can be divided into three broad categories: surgical excision, local radiation therapy (radiotherapy) and chemotherapy drug use, or chemotherapy. When the tumor is only limited to a body organ or tissue, the doctor may use surgery or irradiation for local control; when larger or the cancer cell invasion of distant metastases occur, the would rely on chemical treatment the.
So, how chemotherapy drugs to control cancer effects?
Normal human cell growth, differentiation and death are subject to very strict control, and cancer cells produce the event of disease, its growth will be out of control. Cell growth in the anticancer drug is to be given every step of the treatment to inhibit or kill cancer cells. Anti-cancer drugs, the role of this treatment are mostly in control of cell growth control of chromosome (DNA), so that the chromosomes of cancer cells can not continue the destruction Ershi cell division eventually leading to death. The efficacy of chemotherapy and radiation to some extent similar treatment. When used in conjunction with chemotherapy is usually several drugs with different mechanisms, hoping to kill the cancer cells of different mechanisms to enhance the effect of chemotherapy. The combined use of multiple drug therapy is most commonly appear chemotherapy treatment.
Cancer chemotherapy as a primary treatment can also be a supplementary treatment. Drug treatment can 1) cure some cancer, 2) slow down the growth of cancer cells, 3) reduce the proliferation of cancer cells, 4) to alleviate the discomfort caused by cancer. Especially when some of the tumor cells in the condition was diagnosed when distant metastasis has occurred, then the only body within the play in the treatment of treatment is chemotherapy. For example, the late B-type lymphoma, the disease may be systemic after the lymphoid tissues throughout the lymphoma cells will have only received local radiotherapy to the patient's condition and the effect can not be cured. If patients do not receive chemotherapy treatment often quickly die due to infection or bleeding; in a variety of drugs currently used in integrated programs with only chemotherapy, most patients get relief, including a substantial proportion of patients can be cured . Lymphoma and leukemia's progress in the treatment of chemotherapy most attributable to new drugs or drug combinations of the invention.
Chemotherapy can be used in addition to the direct treatment of cancer, would also be a supplement to treatment and surgery or radiation therapy combined. Part of cancer chemotherapy can reduce the acceptance of cancer recurrence after surgery or delay the recurrence rate of cancer patients and raise the success rate of surgery. Post-operative adjuvant chemotherapy in many cancer treatments have become an integral part, which includes breast cancer, colon cancer and bone cancer after surgery and so on. For example, if patients with colorectal cancer found in lymph node involvement after surgery, the surgery required to continue to receive chemotherapy for their recurrence rate from 60% down to 40 percent, and raise the cure rate.
In addition to their chemotherapy as postoperative adjuvant treatment of cancer to improve cancer cure rate, the chemical treatment can also be used in the surgical resection required to come to surgery to reduce the scope of this use of chemical treatment can be found in the treatment of breast cancer and bone cancer may only be made more breast cancer can be removed from the whole breast or limb bone cancer patients free from amputation. Chemotherapy also can be used as auxiliary treatment of cancer radiation therapy to enhance the efficacy of radiotherapy, such integration treatment Fang Shi Zai Ai's treatment of Jin Bu anal or even better than Le Chuan Tong surgical treatment Shi Zhe Lei Huanzhebuzai Xu Guang Fan of receiving anal excision and to rely on artificial anus pain.
Cancer is a disease, we need to use anti-cancer drugs to treat it to maintain health or to alleviate pain. Also treat other diseases such as hypertension and diabetes drug used as treatment for cancer also has its side effects. Clinical studies continue to make physicians more aware of these side effects and further to adopt various methods to prevent or mitigate these side effects. Chemical treatment advances have led to Chemotherapy for cancer than the direct application as a cancer treatment Yi Jianqinghuanzhe discomfort or extend outside its Sheng Ming, recently before the surgery or radiotherapy or after adjuvant therapy progress Yejiaqiangle surgery or radiotherapy. Cancer chemotherapy is a major factor in successful treatment, surgery and radiation treatment of advances that patients are given better treatment Fang Shi Lai Jubu treatment of cancer, Erzai chemical 药物 cancer treatment and sustained to Zhenzheng on cancer survival in patients with more help.
Q: When chemotherapy will also harm the human body and the normal organ function?
Chemotherapy in the treatment of cancer cells while harming normal human organs. But the side effects of chemotherapy are often temporary. Chemical drugs are used to kill cancer cells. But not all of the chemotherapy drug specificity 100%, so kill cancer cells while normal cells of the human body there are certain other harm role. The most common side effects are usually found in the body usually more vigorous metabolic organs, such as hair, oral mucosa, gastrointestinal tract, bone marrow. Most chemotherapy-induced side effects after treatment can be fully restored.
Q: What are the side effects of cancer chemotherapy?
Cancer chemotherapy is to use the mechanism of inhibition of cell growth to achieve the effect of killing tumor cells. However, chemicals may also be due to similar mechanisms of injury to normal cells, causing the patient's adverse reactions. A brief general common side effects of chemotherapy.
1, inhibition of bone marrow hematopoietic system. In vivo bone marrow hematopoietic cells is one of the strongest cell regeneration, so the most vulnerable to the impact of chemicals. Hematopoietic system is inhibited, the patient may be due to neutropenia and fever caused by inhibition of infection and red blood cells produced by anemia, or thrombocytopenia caused by the bleeding, but have to accept blood transfusions and antibiotics. In recent years, as broad-spectrum antibiotics and the strong development of white blood cell growth hormone, so low white blood cell count caused by infection was greatly improved.
2, nausea and vomiting. Many chemical substances will stimulate the central nervous system or gastrointestinal tract cells, cause nausea and vomiting. Severe vomiting often makes patients fear and refused to accept chemotherapy. Conventional antiemetic agents about 40-50% of the patients can control the vomiting, but necessary to use large doses, often combined neurological side effects such as restlessness and involuntary movements. In recent years, new developments out of 5-HT3 antagonist Picking, can effectively control 60-80% of patients vomiting, and mild side effects, has made chemotherapy-induced nausea and vomiting are fairly good control.
III stomatitis. About 40% of patients will occur in the chemical treatment of oral ulcers, particularly those suffering from hematologic malignancies. Mechanism may occur because of chemical drugs on the oral epithelial cell injury, or infection caused due to neutropenia. Stomatitis patients often feel severe pain, and can not eat. Drug treatment of pain in general is to strengthen the local dental cleaning, if necessary, antibiotics to control infection, and intravenous nutrients to maintain the patient's nutritional status. Most patients in the supportive treatment can resume.
4, hair loss. Is also due to hair cell regeneration with a split, it will be the impact of chemicals fall. Hair although not to the patient's physiological effects, it is usually affect the appearance and the psychological harm to patients. However, after the chemical treatment, long hair will gradually return, and chemical treatment may be more black than bright.
5, other side effects. Different chemical drugs often will damage different organs. Such as adriamycin commonly known as cranberry, novantrone commonly known as small blueberries if overdose may result in heart failure; cisplatin are nephrotoxicity; bleomycin can cause pulmonary fibrosis; high-dose cyclophosphamide causes hemorrhagic cystitis; oncovin and taxol paclitaxel have peripheral nerve toxicity and so on. Therefore, before the use of chemical drugs, they should do so may result in organ damage assessment, and should be followed up regularly during chemotherapy. When the cumulative dose of drugs had reached the limit, or organ function decline significantly, should the withdrawal, in order to avoid serious organ damage.
Like a sharp knife on both sides of chemical drugs, can kill tumor cells, may also harm normal tissue. Depends on the proper use of tumor specific physician, medical treatment can be achieved without pernicious to health effects. Patient without fear of side effects of chemotherapy, to refuse treatment, but should take the initiative to understand the possible side effects encountered and the response of the Road. As for health care workers should actively educating patients so that patients can not be afraid of chemotherapy, and more cooperative, so that treatment can proceed smoothly.
No comments:
Post a Comment